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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T3470 | Cis-ACBD | cis-1-aminocyclobutane-1,3-dicarboxylic acid | Amino Acids and Derivatives |
Cis-ACBD (cis-1-aminocyclobutane-1,3-dicarboxylic acid) is a potent and selective N-methyl-D-aspartate receptor agonist. | |||
T0313 | Evans blue | Direct Blue 53,C.I. 23860 | GluR |
Evans blue (C.I. 23860) is an azo dye, inhibits L-glutamate uptake via the membrane-bound excitatory amino acid transporter (EAAT). | |||
T13536 | Afoxolaner | Chloride channel , GABA Receptor , Parasite | |
Afoxolaner is an isoxazoline insecticide/acaricide against Ixodes scapularis in dogs. Afoxolaner acts on the insect GABA and glutamate receptors, inhibiting GABA & glutamate-regulated uptake of chloride ions, resulting i... | |||
T0267 | Zonisamide | AD 810,CI 912 | Calcium Channel , Sodium Channel , Carbonic Anhydrase |
Zonisamide (AD 810), a sulfonamide anticonvulsant, is approved for use as an adjunctive treatment in adults with partial-onset seizures. It may inhibit a carbonic anhydrase although this is not one of the main mechanisms... | |||
T22043 | BCATc Inhibitor 2 | Others | |
BCATc Inhibitor 2 exhibited an IC50 of 0.8 microM in the hBCATc assays; it is an active and selective inhibitor. BCATc Inhibitor 2 also blocked calcium influx into neuronal cells following inhibition of glutamate uptake,... | |||
T22913 | L-CCG-lll | Others | |
inhibitor of both glial and neuronal uptake of glutamate, aspartate and cysteate. | |||
T29153 | WAY-855 | ||
WAY-855 is an EAAT2-preferring, nonsubstrate inhibitor of high-affinity glutamate uptake. | |||
T22722 | Dihydrokainic acid | Others | |
EAAT2(GLT1)-selective non-transportable inhibitor of L-glutamate and L-aspartate uptake | |||
T11055 | DL-TBOA | transporter | |
DL-TBOA inhibited [14C] glutamate uptake in COS-1 cells expressing human EAAT1 and EAAT2, with Ki values of 42 μM and 5.7 μM, respectively. DL-TBOA blocks EAAT4 and EAAT5 in a competitive manner, with Ki values of 4.4 μM... | |||
T39510 | DL-TBOA ammonium | ||
DL-TBOA ammonium is a potent, non-transportable inhibitor of excitatory amino acid transporters. Its inhibitory effects are demonstrated by IC50 values of 70 μM, 6 μM, and 6 μM for excitatory amino acid transporter-1 (EA... |